Detail zboží

Canine and Feline Liver Cytology připravuje se

Stručný popis

Publikace je praktickou a ilustrovaná příručkou s podrobným popisem cytologických rysů jaterních onemocnění a četnými vysoce kvalitními ilustracemi, které pomohou čtenáři lépe pochopit problematiku onemocnění jater. Primárním cílem textu je popsat korelaci cytologických nálezů s patologickými procesy s cílem poskytnout klinickým lékařům užitečné informace v léčbě jaterních onemocnění.
Publikace obsahuje informace o:
Obecných východiscích pro interpretaci jaterní cytologie, s uvedením limitů cytologie.
Významu cytologie jater pro definitivní diagnózu a vztah ke klinickým výsledkům.
Specifických reverzibilních poškozeních hepatocytů zahrnující hepatocelulární edém, steroidy indukovanou hepatopatii, hepatocelulární steatózu a degeneraci jater.
Nevratném poškození hepatocytů, zahrnující nekrózu, apoptózu, zánět jater, neutrofilní, eozinofilní, makrofagický a lymfoplasmacytický zánět.
Intra a extracytoplazmatických patologických akumulacích zahrnující lipofuscin, měď, železo, eozinofilní granule, proteinové kapénky, žluč a amyloid.
Chronických onemocněních jater se zaměřením na cytologické znaky fibrózy.
Nemocích žlučových cest a žlučníku.
Neoplastických onemocněních pokrývající epiteliální, mezenchymální a kulatobuněčné nádory.
Publikace umožňuje čtenářům interpretovat všechny cytopatologické změny jater se vztahem ke klinickým primárním a sekundárním příčinám, případně s histopatologickou diagnózou, Publikaci je vysoce ceněna jako významný zdroj informací pro veterinární lékaře a studenty.

Autor: Carlo Masserdotti

Cena s DPH: asi 3483 Kč

Zboží není skladem

Koupit

Přesná cena bude sdělena na základě Vaší nezávazné objednávky.

Základní informace

Nakladatel	Wiley-Blackwell
ISBN	9781119895541
Vydání	2024
Vazba	pevná
Počet stran	288

Popis

Specialist reference with practical guidance on liver pathology in a clinical and anatomical context

Canine and Feline Liver Cytology is a practical and highly illustrated manual with detailed descriptions of cytological features of hepatic diseases and numerous high-quality illustrations to aid in reader comprehension. The primary aim of the text is to describe the correlation of cytological findings with pathological processes in order to provide useful information to clinicians in management of hepatic diseases.

Canine and Feline Liver Cytology includes information on:

General bases for interpretation of hepatic cytology, covering limits of cytology, value of cytology for a definitive diagnosis, and relationship with clinical data
A specific reversible injury to hepatocytes, covering hepatocellular swelling, steroid induced hepatopathy, hepatocellular steatosis, and feathery degeneration
Irreversible injury to hepatocytes, covering necrosis and apoptosis, and inflammation, covering neutrophilic, eosinophilic, macrophagic, and lymphoplasmacytic inflammation
Intra and extracytoplasmic pathologic accumulation, covering lipofuscin, copper, iron, eosinophilic granules, protein droplet, bile, and amyloid
Chronic hepatic diseases, with focus on cytological features of fibrosis
Diseases of biliary tract and gallbladder
Neoplastic diseases, covering epithelial, mesenchymal and round cell tumors
Canine and Feline Liver Cytology enables readers to interpret all the cytopathological changes in liver pathology and the relationship with clinical primary and secondary causes, eventually with histopathological diagnosis, making it a highly valuable resource for veterinary practitioners and students.
ABOUT THE AUTHOR
Carlo Masserdotti, DVM, Dipl ECVCP, Spec Bioch Clin IAT, Consultant, Anatomic and Clinical Pathology, IDEXX Laboratories, Brescia, Italy.

Obsah

About the Author	ix
Foreword	xi
Preface	xiii
Acknowledgments	xv
1 Before the Analysis: Rules for Interpretation of Hepatic Cytology	1
1.1 The Rules for Cytological Diagnosis of Hepatic Diseases	2
1.1.1 Rule 1	2
1.1.3 Rule 3	2
1.1.4 Rule 4	3
1.1.5 Rule 5	3
1.1.6 Rule 6	3
1.1.7 Rule 7	4
1.1.8 Rule 8	4
1.2 Diagnostic Approach to Liver Disease	4
1.2.1 Clinical and Anamnestic Signs	5
1.2.2 Hematochemical Investigation	5
1.2.2.1 Pathological Bases of Liver Damage	5
1.2.2.2 Diagnosis of Liver Damage	8
1.2.2.3 Useful Enzymes for Recognition of Damage to Hepatocytes and Cholangiocytes	9
1.2.2.4 Liver Failure Diagnosis	11
1.2.2.5 Parameters of Liver Failure	12
1.2.3 Ultrasonographic Investigation	14
1.2.4 Cytological and Histopathological Investigation	15
1.2.4.1 Sample Collection	15
1.2.4.2 Cytological Approach to Hepatic Diseases	16
1.3 Key Points	16
References	17
2 Normal Histology and Cytology of the Liver	19
2.1 Normal Histology of the Liver	19
2.2 Normal Cytology of the Liver	27
2.2.1 Hepatocytes	28
2.2.2 Kupffer Cells	30
2.2.3 Stellate Cells (Ito Cells)	31
2.2.4 Cholangiocytes (Biliary Cells)	32
2.2.5 Hepatic Lymphocytes	33
2.2.6 Hepatic Mast Cells	34
2.2.7 Hematopoietic Cells	34
2.2.8 Mesothelial Cells	36
2.3 Key Points	38
References	39
3 Nonspecific and Reversible Hepatocellular Damage	41
3.1 Accumulation of Water	42
3.2 Accumulation of Glycogen	43
3.3 Accumulation of Lipids	46
3.4 Accumulation of Bilirubin and Bile Salts	57
3.5 Hyperplasia of Stellate Cells	57
3.6 Regenerative Changes	59
3.7 Key Points	64
References	64
4 Intracytoplasmic and Extracytoplasmic Pathological Accumulation	67
4.1 Pathological Intracytoplasmic Accumulation	67
4.1.1 Lipofuscin	67
4.1.2 Copper	73
4.1.3 Iron and Hemosiderin	76
4.1.4 Protein Droplets	82
4.1.5 Cytoplasmic Granular Eosinophilic Material	82
4.1.6 Hepatic Lysosomal Storage Disorders	85
4.2 Pathological Extracytoplasmic Accumulation	86
4.2.1 Bile	86
4.2.2 Amyloid	90
4.3 Key Points	96
References	96
5 Irreversible Hepatocellular Damage	101
5.1 Necrosis	101
5.2 Apoptosis	107
5.3 Key Points	110
References	110
6 Inflammation	113
6.1 Presence of Neutrophilic Granulocytes	115
6.2 Presence of Eosinophilic Granulocytes	123
6.3 Presence of Lymphocytes and Plasma Cells	125
6.4 Presence of Macrophages	130
6.5 Presence of Mast Cells	137
6.6 Key Points	139
References	139
7 Nuclear Inclusions	143
7.1 “Brick” Inclusions	143
7.2 Glycogen Pseudo-inclusions	144
7.3 Lead Inclusions	146
7.4 Viral Inclusions	146
7.5 Key Points	147
References	147
8 Cytological Features of Liver Fibrosis	149
8.1 Cytological Features of Liver Fibrosis	150
8.2 Key Points	159
References	160
9 Cytological Features of Biliary Diseases	163
9.1 General Features of Biliary Diseases	165
9.2 Cytological Features of Specific Biliary Diseases	167
9.2.1 Acute and Chronic Cholestasis	167
9.2.2 Acute Cholangitis	170
9.2.3 Chronic Cholangitis	170
9.2.4 Lymphocytic Cholangitis	170
9.3 Key Points	175
References	175
10 Bile and Gallbladder Diseases	177
10.1 Bactibilia and Septic Cholecystitis	179
10.2 Epithelial Hyperplasia	181
10.3 Gallbladder Mucocele	181
10.4 Limy Bile Syndrome	183
10.5 Biliary Sludge	183
10.6 Neoplastic Diseases of Gallbladder	183
10.7 Other Gallbladder Diseases	184
10.8 Key Points	184
References	184
11 Etiological Agents	187
11.1 Viruses	188
11.2 Bacteria	189
11.3 Protozoa	193
11.4 Fungi	194
11.5 Parasites	194
11.6 Key Points	197
References	197
12 Neoplastic Lesions of the Hepatic Parenchyma	199
12.1 Epithelial Neoplasia	200
12.1.1 Nodular Hyperplasia	200
12.1.2 Hepatocellular Adenoma	204
12.1.3 Hepatocellular Carcinoma	206
12.1.4 Cholangioma	215
12.1.5 Cholangiocellular Carcinoma	217
12.1.6 Other Nodular Lesions of Biliary Origin	222
12.1.7 Hepatic Carcinoid	223
12.1.8 Hepatoblastoma	227
12.2 Mesenchymal Neoplasia	227
12.2.1 Malignant Mesenchymal Neoplasms	227
12.3 Hematopoietic Neoplasia	229
12.3.1 Myelolipoma	231
12.3.2 Large Cell Hepatic Lymphoma	232
12.3.3 Small Cell Lymphoma	234
12.3.4 Large Granular Lymphocyte (LGL) Lymphoma	236
12.3.5 Epitheliotropic Lymphoma	239
12.3.6 Other Types of Hepatic Lymphoma	240
12.3.7 Malignant Histiocytic Neoplasms	242
12.3.8 Mast Cell Tumor	245
12.3.9 Hepatic Splenosis	247
12.4 Metastatic Neoplasia	247
12.5 Criteria for Selection of Sampling Methods for Liver Nodular Lesions	248
12.6 Key Points	250
References	250
Index	255