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Lactogenic immunity in the sow a practical approach

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Publikace se zabývá problematikou laktogenní imunity u prasnic a následně selat. Čtenář po prostudování této publikace určitě lépe porozumí dané problematice.

Autor: Fraile Sauce, Lorenzo José

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Počet stran144

Good transfer of passive immunity from sows to piglets is crucial to ensure piglet survival on pig farms. This book is intended to help veterinary practitioners work towards this goal, and includes a review of the basics of immunology and vaccination, as well as comprehensive chapters on the immunisation programmes used in sows and on the transfer of passive immunity from sows to piglets.
Lorenzo José Fraile Sauce Degree in Veterinary Medicine (1992) and Doctor of Veterinary Pharmacology in 1996, both from the University of Zaragoza, Spain, then specialist pig vet for Cargill España S.A. and Picber S.A. until 2004. Researcher at the Centre de Recerca en Sanitat Animal (CReSA; Centre for Animal Health Research) from 2004 to 2010, where he was head of the Department of Epidemiology, Disease Control and Clinical Trials. Collaborator with the European Medicines Agency from 2005 to 2007, assessing veterinary medicines submitted for registration in Europe through his work on the Committee for Medicinal Products for Veterinary Use (CVMP). Member of the Scientific Advice Group on Antimicrobials, which provides scientific advice on all aspects of the use of antimicrobials in veterinary medicine to CVMP, from 2006 to 2007. Adjunct professor of Epidemiology and Pharmacology at the University of Lleida since 2010, and involved in teaching the Masters Degree in Swine Production and Health offered by the Complutense University of Madrid, the University of Lleida and the University of Zaragoza. His current fields of scientific interest are epidemiology, immunology and clinical pharmacology, and his research aims to optimise preventative medicine programmes in pigs. He is the author of over 80 articles published in international scientific journals and 130 papers presented at national and international conferences. Finally, he has been a speaker at many veterinary conventions.

Basic immunological concepts3
Innate immunity5
Cellular component8
Humoral component10
Adaptive (acquired) immunity11
Humoral component16
Cellular component16
Dynamics of the immune response20
Relative importance of cellular and humoral immunity in effective protection23
2. General principles of vaccines and vaccination25
Methods of active artificial immunisation30
Practical vaccine application35
Adverse reactions to vaccines39
3. Transfer of passive immunity to the piglet43
Passive immunity and its role in the piglet45
Colostrum, transient milk and mature milk45
The role of colostrum in newborn piglet survival46
Transfer of humoral and cellular immunity51
Humoral immunity52
Cellular immunity56
ategy for improving the transfer of passive immunity58
Interference with active immunity by passive immunity60
Interference with the development of humoral immunity61
Interference with the development of cellular immunity66
Strategies to overcome maternal immunity and develop effective active immunity in the newborn69
4. Prevention programmes in pigs73
Basic concepts75
Bacterial diseases: sow vaccination programmes75
Vaccination against exotoxin–producing bacteria79
Vaccination against extracellular bacteria79
Viral diseases: sow vaccination programmes93
Vaccination against porcine reproductive and respiratory syndrome95
Vaccination against porcine circovirus disease97
Vaccination against parvovirus infection102
Vaccination against swine influenza102
5. Practical aspects of the transfer of passive immunity to the piglet109
Management of colostrum consumption1111
Factors related to quality111
Factors related to quantity112
Measuring the transfer of passive immunity113