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Autoři čtenářúm této publikace předložili stručný přehled na metabolicky-endokrinní fyziologii. V publikaci autoři kladli důraz na instruktážní údaje, diagramy a přehledné tabulky s mininem textu tak, aby daná problematika byla přehledná a lehce pochopitelná. V úvodní kapitole je endokrinní systém stručně definován a v následujících kapitolách je popsána každá endokrinní žláza samostatně. V textu jsou uvedeny i známé a nejčastější endokrinní poruchy. V textu jsou srozumitelně popsány mechanizmy zodpovědné za udržování homeostatické kontroly významných fyziologických funkcí. Publikace je doplněna více jak 360 otázkami, které umožňují prověřit vědomosti uživatele.
Autor: Larry Engelking:
Nakladatel | Teton NewMedia |
---|---|
ISBN | 9781591610465 |
Vydání | 2012 |
Vazba | brožovaná |
Počet stran | 210 |
This book is intended to give readers a “quick look” at metabolic and endocrine physiology. Emphasis is placed on instructional figures, flow diagrams and tables, while text material has been held to a minimum. In general, the endocrine system is first defined and described, and then each endocrine gland is discussed separately. Where appropriate, common endocrine disorders have also been included. This text concisely elucidates the endocrine mechanisms responsible for maintaining homeostatic control of important physiologic variables, and to assist the reader in understanding common pathophysiologic deviations from normal. Over 360 multiple-choice questions gauge the reader’s capacity to effectively understand the subject material.
This new edition contains six new chapters covering: hormone disposition, measurement and secretion; bovine, equine and rodent estrus cycles; primate menstrual cycle; male reproductive system; testosterone, estrogen and progesterone; comparative aspects of endocrinology. Learning objectives have been added at the beginning of each chapter and all of the questions are new.
Endocrine System | 2 |
Overview | 2 |
Endocrine Secretory Control | 4 |
Autocrine, Paracrine, and Endocrine Mediators | 4 |
Hormone Disposition, Measurement and Secretion | 6 |
Production & Distribution Volume,Clearance & Immunoassay | 6 |
Mechanisms of Catecholamine and Polypeptide Hormone Action: I | 8 |
Receptors and Second Messengers | 8 |
Mechanisms of Catecholamine and Polypeptide Hormone Action: II | 10 |
The Intracellular Ca2+/DG Messenger System | 10 |
Steroid and Thyroid Hormones | 12 |
Mechanisms of Action | 12 |
Hypothalamus and Pituitary | 14 |
Directors of the Endocrine Orchestra | 14 |
Proopiomelanocortin and Related Peptides: I | 16 |
Endogenous Opiate-Like Peptides | 16 |
Proopiomelanocortin and Related Peptides: II | 18 |
Melanocyte-Stimulating Hormone | 18 |
Growth Hormone: I | 20 |
Actions and Secretory Control | 20 |
Growth Hormone: II | 22 |
Hypo- and Hypersomatotropism | 22 |
Antidiuretic Hormone | 24 |
Vasopressin | 24 |
Diabetes Insipidus | 26 |
Central and Nephrogenic | 26 |
Calcium | 28 |
Physiologic Actions. | 28 |
Magnesium and phosphate | 30 |
Physiologic Actions | 30 |
Parathormone, Calcitonin, and Vitamin D: I | 32 |
PTH, PTHrp, and CT | 32 |
Parathormone, Calcitonin, and Vitamin D: II | 34 |
CT and 1,25(OH)2D | 34 |
Disorders of Calcium Homeostasis | 36 |
Hyper- and Hypocalcemia | 36 |
Mineral Imbalances: I | 38 |
Na+, K+, PO43, and Mg2+ | 38 |
Mineral Imbalances: II | 40 |
Parturient Hypocalcemia and Osteoporosis | 40 |
ACTH and Glucocorticoids: I | 42 |
Corticosteroidogenesis and Degradation | 42 |
ACTH and Glucocorticoids: II | 44 |
ACTH Secretion and Action | 44 |
ACTH and Glucocorticoids: III | 46 |
Organ and Tissue Effects) | 46 |
Physiologic and Pharmacologic Actions | 48 |
Cushing's-Like Syndrome and Disease | 50 |
Glucocorticoid Excess | 50 |
Mineralocorticoids | 52 |
Effects on Na+, K+ and H+ | 52 |
Renin-Angiotensin System: I | 54 |
The Juxtaglomerular Apparatus | 54 |
Renin-Angiotensin System: II | 56 |
Hypertension | 56 |
Addison’s-Like Disease | 58 |
Hypoadrenocorticism | 58 |
Erythropoietin | 60 |
Production and Action | 60 |
Natriuretic Peptides | 62 |
ANP, BNP, CNP, and Urodilatin | 62 |
Adrenal Medulla: I | 64 |
Catecholamine Biosynthesis and Degradation | 64 |
Adrenal Medulla: II | 66 |
Adrenergic Receptors and the Sympathoadrenal Response | 66 |
Pheochromocytoma | 68 |
Catecholamine-Secreting Tumor | 68 |
Phasic Responses to Trauma | 70 |
Immediate, Catabolic, and Anabolic | 70 |
Thyroid: I | 72 |
Hormone Biosynthesis and Secretory Regulation | 72 |
Thyroid: II | 74 |
Metabolic Effects of Thyroid Hormones | 74 |
Hypothyroidism | 76 |
Signs and Symptoms | 76 |
Hyperthyroidism | 78 |
Signs and Symptoms | 78 |
Endocrine Pancreas: I | 80 |
The Islets of Langerhans | 80 |
Endocrine Pancreas: II | 82 |
Regulation of Insulin Release | 82 |
Insulin | 84 |
Actions and Degradation | 84 |
Glucagon | 86 |
Biosynthesis and Metabolic Actions | 86 |
Diabetes Mellitus | 88 |
The “Pissing Evil" | 88 |
Acute Insulin Withdrawal: I | 90 |
Carbohydrate and Lipid Metabolism | 90 |
Acute Insulin Withdrawal: II | 92 |
Protein Metabolism and Electrolyte Depletion | 92 |
Gastrointestinal Hormones: I | 94 |
Introduction and Historical Perspective | 94 |
Gastrointestinal Hormones: II | 96 |
Gastrins | 96 |
Gastrointestinal Hormones: III | 98 |
Gastric HCl Secretion, and CCK | 98 |
Gastrointestinal Hormones: IV | 100 |
Secretin and other GI Peptides | 100 |
APUDomas | 102 |
Neuroendocrine Tumors of the Gut) | 102 |
Reproductive Endocrinology | 104 |
Introduction | 104 |
Estrous Cycles | 106 |
Types and Phases | 106 |
Endocrine Parameters | 108 |
Bovine, Equine and Rodent Estrous Cycles | 110 |
Endocrine Parameters | 110 |
Primate Menstrual Cycle | 112 |
Endocrine Parameters | 112 |
Menstruation and Regulation of Gonadotropin Release | 114 |
Control of the GnRH Pulse Generator | 114 |
Spermatogenesis and Ovulation | 116 |
Gonadotropin Control | 116 |
Male Reproductive System | 118 |
The Testes and Accessory Sex Glands | 118 |
Testosterone, Estrogen and Progesterone | 120 |
Biosynthesis, Metabolism and Functions | 120 |
Pineal Gland: I | 122 |
Photoperiodic Regulation of Reproductive Events | 122 |
Pineal Gland: II | 124 |
Nonreproductive Actions of Melatonin | 124 |
Placental Hormones | 126 |
Fertilization, the CL and Placenta | 126 |
Fetal Endocrine System: I | 128 |
The Fetoplacental Unit | 128 |
Fetal Endocrine System: II | 130 |
Glandular Development | 130 |
Maternal Endocrine System | 132 |
Functional Alterations during Pregnancy. | 132 |
Maternal Organ Systems | 134 |
Patterns of Change | 134 |
Mammary Glands | 136 |
Mammogenesis and Lactation | 136 |
Prolactin | 138 |
Secretory Control and Physiologic Actions | 138 |
Oxytocin | 140 |
Physiologic Actions | 140 |
Neonatal Physiology: I | 142 |
Thermal, Nutritional, and Cardiovascular Adaptations) | 142 |
Neonatal Physiology: II | 144 |
Organ System Development | 144 |
Comparative Aspects of Endocrinology | 146 |
Appendix Table I | 153 |
Blood Chemistry Values for Domestic Animals | 153 |
Appendix Table II | 155 |
Reproductive Patterns of Domestic Animals | 155 |
Appendix Table III | 156 |
Basic Physiological Units | 156 |
Learning Objectives, | 157 |
Study Questions and Answers | 157 |
References | 197 |
Index | 202 |