Veterinary Clinics of North America: Food Animal Practice: Ruminant Ophthalmology
Stručný popis
Kolektiv autorů se zabývá problematikou infekčních onemocnění skotu. V jednotlivých kapitolách se uvedeny nové poznatky o diagnostice, terapii a prevencí oftalmologických onemocnění. Zajímavé jsou kapitoly o ekonomickém dopadu na produkci potravin a výhled do budoucích terapeutických možností u těchto infekčních onemocnění skotu.
Autor: Annette M. O’Connor
Cena s DPH: asi 2136 Kč
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Základní informace
| Nakladatel | Elsevier Saunders |
|---|---|
| ISBN | 9780323813150 |
| Vydání | 2021 |
| Vazba | pevná |
| Počet stran | 142 |
Obsah
| Defining and Diagnosing Infectious Bovine Keratoconjunctivitis | 237 |
| Key points | 237 |
| Introduction | 237 |
| Definition of infectious bovine keratoconjunctivitis | 238 |
| Diagnosis of infectious bovine keratoconjunctivitis | 238 |
| Clinical subclassification and infectious bovine keratoconjunctivitis scores | 248 |
| Summary | 248 |
| Clinics care points | 249 |
| Bovine Immune Responses to Moraxella bovis and Moraxella bovoculi Following Vaccination and Natural or Experimental Infections | 253 |
| Key points | 253 |
| Introduction | 253 |
| Overview of bovine ocular immune responses | 254 |
| Immune responses to Moraxella antigens | 256 |
| Evidence for protective immune responses to Moraxella antigens | 261 |
| Evidence for harmful immune responses to Moraxella antigens | 262 |
| Summary | 262 |
| Clinics care points | 263 |
| Applying Concepts of Causal Inference to Infectious Bovine Keratoconjunctivitis | 267 |
| Key points | 267 |
| Introduction | 267 |
| Causal frameworks | 267 |
| Bradford Hill viewpoints applied to Moraxella bovis, Moraxella bovoculi, and infectious bovine keratoconjunctivitis | 269 |
| Summary | 275 |
| Component Causes of Infectious Bovine Keratoconjunctivitis - The Role of Moraxella Species in the Epidemiology of Infectious Bovine Keratoconjunctivitis | 279 |
| Key points | 279 |
| Introduction | 279 |
| Moraxella bovis- virulence factors | 280 |
| Moraxella bovis pili | 280 |
| Moraxella bovis other potential virulence factors | 283 |
| Studies on Moraxella bovis and causality | 283 |
| Moraxella bovis genomics | 284 |
| Moraxella bovoculi | 284 |
| Challenge models | 285 |
| Moraxella bovoculi and causality | 286 |
| Moraxella bovoculi genomics | 286 |
| Classification of Moraxella bovis and Moraxella bovoculi | 287 |
| Summary and future work | 287 |
| Clinics care points- diagnosis and establishment of Moraxella etiology in infectious bovine keratoconjunctivitis | 287 |
| Disclosure | 287 |
| Component Causes of Infectious Bovine Keratoconjunctivitis—Non-Moraxella Organisms in the Epidemiology of Infectious Bovine Keratoconjunctivitis | 295 |
| Key points | 295 |
| Introduction | 295 |
| Virulence factors | 297 |
| Clinical disease | 297 |
| Immunity | 298 |
| Epidemiologic studies | 299 |
| Other mycoplasmas | 300 |
| Herpesviruses | 300 |
| Summary | 302 |
| Clinics care points | 303 |
| Disclosure | 303 |
| The Role of Environmental Factors in the Epidemiology of Infectious Bovine Keratoconjunctivitis | 309 |
| Key points | 309 |
| Introduction | 309 |
| Face flies | 310 |
| Ultraviolet light | 316 |
| Plant awns | 317 |
| Clinics care points | 317 |
| Component Causes of Infectious Bovine Keratoconjunctivitis: The Role of Genetic Factors in the Epidemiology of Infectious Bovine Keratoconjunctivitis | 321 |
| Key points | 321 |
| Introduction | 321 |
| Heritability estimates | 322 |
| Loci associated with infectious bovine keratoconjunctivitis | 324 |
| Summary | 325 |
| Evidence Base for Treatment of Infectious Bovine Keratoconjunctivitis | 329 |
| Key points | 329 |
| Background | 329 |
| North American registered antibiotic treatments for infectious bovine keratoconjunctivitis | 330 |
| Other treatments for infectious bovine keratoconjunctivitis | 331 |
| Developing an evidence base for treatments of infectious bovine keratoconjunctivitis | 332 |
| Clinical equipoise | 333 |
| What should the referent comparison be? | 333 |
| What should be the experimental comparator? | 334 |
| What is the alternative hypothesis? | 334 |
| Artificially induced disease or naturally occurring disease | 334 |
| Approach to allocation to treatment | 334 |
| What outcome to assess | 335 |
| Summary | 338 |
| The Evidence Base for Prevention of Infectious Bovine Keratoconjunctivitis Through Vaccination | 341 |
| Key points | 341 |
| Introduction | 341 |
| Possible vaccine targets for Moraxella bovis | 342 |
| Local versus systemic immune responses | 343 |
| Prevention of Moraxella bovis infection of the cornea or elimination of the carrier status | 344 |
| The role of maternal antibodies and transfer of passive immunity | 344 |
| Efficacy of commercially available vaccines for infectious bovine keratoconjunctivitis | 344 |
| Efficacy of experimental vaccination | 344 |
| Failure of results from experimental vaccines to translate to commercial products | 346 |
| Quality assessment of vaccine trial study design | 347 |
| Outcome metrics for field trials | 348 |
| Summary | 348 |
| Clinics care points | 349 |
| Keratoconjunctivitis | 355 |
| Key points | 355 |
| Introduction | 355 |
| Literature review | 356 |
| Biology of infectious bovine keratoconjunctivitis | 356 |
| Prevalence of infectious bovine keratoconjunctivitis | 357 |
| Global estimate of prevalence | 357 |
| Global economic impact | 363 |
| Summary and implications | 365 |
| Clinics care points | 365 |
| Future Directions for Research in Infectious Bovine Keratoconjunctivitis | 371 |
| Key points | 371 |
| Introduction | 372 |
| Diagnosis | 372 |
| Epidemiology | 372 |
| Economic impact | 373 |
| Prevention | 374 |
| Treatment | 376 |
| General principles | 377 |
| Summary | 378 |